Article
Mucin expression, p53 overexpression, and peritumoral lymphocytic infiltration of advanced colorectal carcinoma with mucus component: is mucinous carcinoma a distinct histological entity?
Pathology, research and practice - 1 Jan 2007
Tozawa Erica, Ajioka Yoichi, Watanabe Hidenobu, Nishikura Ken, Mukai Gen, Suda Takeyasu, Kanoh Tsunehisa, Hatakeyama Katsuyoshi
Abstract excerpt
Mucinous carcinoma of the colorectum is conventionally defined as carcinoma with an interstitial mucus component (MC) that occupies more than 50% of the tumor tissue. To examine the validity of this definition, we quantified the ratio between the area of MC and the total area of carcinoma (MC ratio) in 152 advanced colorectal carcinomas, and investigated whether MUC1, MUC2 and MUC5AC mucin expression, frequency...
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