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Article

Permanent hexose transport upregulation in a respiration-deficient human fibroblast cell strain.

The American journal of physiology - 1 Dec 1991

Andrejchyshyn S, Continelli L, Germinario R J

Abstract excerpt

The regulation of hexose transport was studied in a human diploid fibroblast respiration-deficient cell strain (WG750). Transport of 2-deoxy-D-glucose (2-DG) was greater than sixfold higher compared with an in vivo age-matched normal cell strain (MCH55). In addition, 3-O-methylglucose transport and 14CO2 production were elevated in the mutant cell strain. Kinetic analysis revealed that the increased sugar...

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PMID: 1767824
DOI: 10.1152/ajpcell.1991.261.6.C973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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