Permanent hexose transport upregulation in a respiration-deficient human fibroblast cell strain.

doi:10.1152/ajpcell.1991.261.6.C973

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Article

Permanent hexose transport upregulation in a respiration-deficient human fibroblast cell strain.

The American journal of physiology - 1 Dec 1991

Andrejchyshyn S, Continelli L, Germinario R J

Abstract excerpt

The regulation of hexose transport was studied in a human diploid fibroblast respiration-deficient cell strain (WG750). Transport of 2-deoxy-D-glucose (2-DG) was greater than sixfold higher compared with an in vivo age-matched normal cell strain (MCH55). In addition, 3-O-methylglucose transport a...

Topics

Biological Transport
Blotting, Western
Carbon Dioxide
Cell Line
Deoxyglucose
Diploidy
Fibroblasts
Hexoses
Humans
Insulin
Kinetics
Lactates
Mutation
Oxygen
Up-Regulation

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