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Article

Disease susceptibility of the human macula: differential gene transcription in the retinal pigmented epithelium/choroid.

Experimental eye research - 1 Sept 2007

Radeke Monte J, Peterson Katie E, Johnson Lincoln V, Anderson Don H

Abstract excerpt

The discoveries of gene variants associated with macular diseases have provided valuable insight into their molecular mechanisms, but they have not clarified why the macula is particularly vulnerable to degenerative disease. Its predisposition may be attributable to specialized structural features and/or functional properties of the underlying macular RPE/choroid. To examine the molecular basis for the macula's...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17662275
DOI: 10.1016/j.exer.2007.05.006

Genes

RPE
TFPI2
CXCL14
SLIT2
CCL19
CCL26
DCN
MYOC
OGN
SMOC2
WFDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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