Article
Gly111Ser mutation in CD8A gene causing CD8 immunodeficiency is found in Spanish Gypsies.
Molecular immunology - 1 Jan 2008
Mancebo Esther, Moreno-Pelayo Miguel A, Mencía Angeles, de la Calle-Martín Oscar, Allende Luis M, Sivadorai Padma, Kalaydjieva Luba, Bertranpetit Jaume, Coto Eliecer, Calleja-Antolín Sara, Ruiz-Contreras Jesus, Paz-Artal Estela
Abstract excerpt
We describe the second case of CD8 immunodeficiency. It confirms the pathogenic effect of p.Gly111Ser, leading to complete deficit of CD8+ lymphocytes, although the clinical manifestations may vary in severity. Similarly to the first case reported, our patient is also from Spanish Gypsy origin an...
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