Article
Absence of Y chromosome in human placental site trophoblastic tumor.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2007
Hui Pei, Wang Hanlin L, Chu Peiguo, Yang Bin, Huang Jiaoti, Baergen Rebecca N, Sklar Jeffrey, Yang Ximing J, Soslow Robert A
Abstract excerpt
Placental site trophoblastic tumor is a neoplasm of extravillous intermediate trophoblast at the implantation site, preceded in the majority of cases by a female gestational event. Our pilot investigation suggested that the development of this tumor might require a paternally derived X chromosome and the absence of a Y chromosome. Twenty cases of placental site trophoblastic tumor were included in this study....
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