Article
Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage.
Human reproduction (Oxford, England) - 1 May 2001
Rai R, Shlebak A, Cohen H, Backos M, Holmes Z, Marriott K, Regan L
Abstract excerpt
Activated protein C (APC) resistance, both in its congenital form, due to the factor V Leiden mutation, and in its acquired form, are important risk factors for systemic venous thrombosis. In view of the suspected thrombotic aetiology of some cases of recurrent miscarriage, the prevalence of APC resistance was determined among 1111 consecutive Caucasian women with a history of either recurrent early miscarriage...
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