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Article

Effects of 4-Hydroxy-2-Nonenal, a Marker of Oxidative Stress, on Spermatogenesis and Expression of p53 Protein in Male Infertility

17 Jul 2007

Abstract excerpt

PURPOSE: Oxidative stress is involved in male infertility. However, little is known about how it impairs spermatogenesis. We investigated the presence of oxidative stress in human testes by studying the generation of 4-hydroxy-2-nonenal modified proteins and expressions of proliferating cell nuclear antigen and p53. MATERIALS AND METHODS: A total of 47 testicular biopsies from patients with varicocele,...

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Identifiers

PMID: 17632137
DOI: 10.1016/j.juro.2007.05.027

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