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Smoking Alters Alveolar Macrophage Recognition and Phagocytic Ability

13 Jul 2007

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is associated with defective efferocytosis (apoptosis and alveolar macrophage [AM] phagocytic function) that may lead to secondary necrosis and tissue damage. We investigated ex vivo AM phagocytic ability and recognition molecules (CD36, integrin alphaVbeta3, CD31, CD91, CD44) using flow cytometry. The transferrin receptor (CD71) was measured as an indicator of...

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PMID: 17630319
DOI: 10.1165/rcmb.2007-0025oc

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