Article
Manganese superoxide dismutase (Mn-SOD) gene polymorphisms in urolithiasis.
Urological research - 1 Oct 2007
Tugcu Volkan, Ozbek Emin, Aras Bekir, Arisan Serdar, Caskurlu Turhan, Tasci Ali Ihsan
Abstract excerpt
Polymorphism in manganese superoxide dismutase gene (Mn-SOD) is a new approach to identify its probable association with urolithiasis. Oxidative stress may be involved in the development of stone formation in the renal system. MnSOD is one of the primary enzymes that directly scavenges potential harmful oxidizing species. A valine (Val) to alanine (Ala) substitution at amino acid 16, occurring in the...
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