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Article

Sp1 is required for transcriptional activation of the fibroblast growth factor receptor 1 gene in neonatal cardiomyocytes.

Gene - 1 Oct 2007

Seyed Mahdie, Dimario Joseph X

Abstract excerpt

Fibroblast growth factor receptor 1 (FGFR1) is the predominant FGFR in cardiac tissue and regulates proliferation, differentiation, and maintenance of normal myocardium. During development of cardiac tissue, FGFR1 gene expression regulates cardiomyocyte proliferation. The focus of this study was to determine the molecular mechanism of transcriptional activation of the FGFR1 gene in proliferating neonatal...

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Share to Animals, Newborn
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Rats, Sprague-Dawley

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to Sp1 Transcription Factor

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Source

Identifiers

PMID: 17628354
DOI: 10.1016/j.gene.2007.06.010

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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