Article
Potential causes of linkage disequilibrium in a European maize breeding program investigated with computer simulations.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Aug 2007
Stich Benjamin, Melchinger Albrecht E, Piepho Hans-Peter, Hamrit Sonia, Schipprack Wolfgang, Maurer Hans P, Reif Jochen C
Abstract excerpt
Knowledge about the forces generating and conserving linkage disequilibrium (LD) is important for drawing conclusions about the prospects and limitations of association mapping. The objectives of our research were to examine the importance of (1) selection, (2) mutation, and (3) genetic drift for generating LD in a typical maize breeding program. We conducted computer simulations based on genotypic data of...
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