Article
Interaction of polymorphisms in the interleukin 1B-31 and general transcription factor 2A1 genes on the susceptibility to gastric cancer.
Cytokine - 1 May 2007
Lee Kyung-A, Park Jun Hee, Sohn Tae-Sung, Kim Sung, Rhee Jong-Chul, Kim Jong-Won
Abstract excerpt
Proinflammatory genotypes of the IL-1 (interleukin-1) gene have been associated with an increased gastric cancer risk in Caucasians, whereas some studies in Asian populations did not find such association. Furthermore, the risk genotypes differed somewhat between Caucasian and Asian populations. These findings might reflect more complex genetic mechanisms in Asian compared with Caucasian populations. Therefore,...
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