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Article

Association analysis of glutathione-S-transferase P1 (GSTP1) polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapy.

International journal of urology : official journal of the Japanese Urological Association - 1 Jun 2007

Yokomizo Akira, Yamamoto Ken, Kinukawa Naoko, Tsunoda Toshiyuki, Koga Hirofumi, Naito Seiji

Abstract excerpt

AIM: Glutathione-S-transferase P1 (GSTP1) detoxifies a wide range of endogenous and exogenous carcinogens and anticancer agents such as cisplatin and doxorubicin. The aim of this study was to examine the association between GSTP1 polymorphism and both urothelial cancer susceptibility and adverse events of M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) chemotherapy in Japanese urothelial cancer...

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Source

Identifiers

PMID: 17593093
DOI: 10.1111/j.1442-2042.2007.01769.x

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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