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Article

Mutations in the 3'-untranslated region of GATA4 as molecular hotspots for congenital heart disease (CHD).

BMC medical genetics - 25 Jun 2007

Reamon-Buettner Stella Marie, Cho Si-Hyen, Borlak Juergen

Abstract excerpt

BACKGROUND: The 3'-untranslated region (3'-UTR) of mRNA contains regulatory elements that are essential for the appropriate expression of many genes. These regulatory elements are involved in the control of nuclear transport, polyadenylation status, subcellular targetting as well as rates of translation and degradation of mRNA. Indeed, 3'-UTR mutations have been associated with disease, but frequently this region...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17592645
DOI: 10.1186/1471-2350-8-38
PMCID: PMC1933416

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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