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hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands

5 Jun 2007

Abstract excerpt

BACKGROUND: The normal human prostate glandular epithelium has the unique function of accumulating high levels of zinc. In prostate cancer this capability is lost as an early event in the development of the malignant cells. The mechanism and factors responsible for the ability of the normal epithelial cells to accumulate zinc and the loss of this capability in the malignant cells need to be identified. We...

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PMID: 17550612
DOI: 10.1186/1476-4598-6-37

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