[Host-leukemogenic virus relation: genetic control of the appearance of leukemia].

Article

[Host-leukemogenic virus relation: genetic control of the appearance of leukemia].

Bulletin du cancer - 1 Jan 2000

Lévy J P

Abstract excerpt

A complex genetic system controls the susceptibility to virus induced leukemia. A good example is provided by AKR mice in which several genes acting in association are involved. The control is demonstrable at several levels: a) virus expression, b) virus replication, c) antitumor immune response. In addition one or two other genes could be involved. The "Leukemia-permissive" genotype would be probably rarely...

Topics

Animals
Cell Transformation, Neoplastic
DNA, Viral
Genotype
Humans
Leukemia
Leukemia Virus, Murine
Leukemia, Experimental
Mice
Mice, Inbred AKR
Mutation
Retroviridae

Virus Replication

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