Article
Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study.
Diabetes care - 1 Oct 2007
Meigs James B, Larson Martin G, Fox Caroline S, Keaney John F, Vasan Ramachandran S, Benjamin Emelia J
Abstract excerpt
OBJECTIVE: Systemic oxidative stress causes insulin resistance in rodents. We tested the hypothesis that oxidative stress and insulin resistance are associated in humans. RESEARCH DESIGN AND METHODS: We used cross-sectional data from 2,002 nondiabetic subjects of the community-based Framingham Offspring Study. We measured insulin resistance with the homeostasis model and defined categorical insulin resistance as...
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