Article
Xp11.2 translocation renal cell carcinoma with very aggressive course in five adults.
American journal of clinical pathology - 1 Jul 2007
Meyer Paul N, Clark Joseph I, Flanigan Robert C, Picken Maria M
Abstract excerpt
Renal cell carcinomas associated with Xp11.2 translocations ( TFE3 gene fusions) are rare tumors predominantly reported in children. We studied 5 cases of translocation carcinoma in adult patients, 18 years or older (mean age, 32.6 years). Tumors were examined histologically, immunohistochemically, and electron microscopically and correlated with the clinical picture. Most tumors showed solid sheets of clear to...
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