Article
Rapid differentiation between fluconazole-sensitive and -resistant species of Candida directly from positive blood-culture bottles by real-time PCR.
Journal of medical microbiology - 1 Jul 2007
Metwally L, Hogg G, Coyle P V, Hay R J, Hedderwick S, McCloskey B, O'Neill H J, Ong G M, Thompson G, Webb C H, McMullan R
Abstract excerpt
In view of both the delay in obtaining identification by conventional methods following blood-culture positivity in patients with candidaemia and the close relationship between species and fluconazole (FLC) susceptibility, early speciation of positive blood cultures has the potential to influence therapeutic decisions. The aim was to develop a rapid test to differentiate FLC-resistant from FLC-sensitive Candida...
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