Article
Relevance of microRNAs in normal and malignant development, including human testicular germ cell tumours.
International journal of andrology - 1 Aug 2007
Looijenga L H J, Gillis A J M, Stoop H, Hersmus R, Oosterhuis J W
Abstract excerpt
The dogma of genome functionality has recently been challenged by identification of non-protein-encoding RNAs, including mi(cro)RNAs. These relatively small sequences interact with mRNA and in the mammalian system, are involved in fine-tuning the process of translation. miRNAs have been found to be of crucial importance for normal development, including stem cell formation. Recent interesting fundamental...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.