Article
Genetic interaction and phenotypic analysis of the Arabidopsis MAP kinase pathway mutations mekk1 and mpk4 suggests signaling pathway complexity.
FEBS letters - 10 Jul 2007
Su Shih-Heng, Suarez-Rodriguez Maria Cristina, Krysan Patrick
Abstract excerpt
It has been shown that the Arabidopsis MEK kinase MEKK1 acts upstream of the MAP kinase MPK4 to negatively regulate salicylic acid-dependent defense-response pathways. Here, we report that the mekk1;mpk4 double-mutant combination causes seedling lethality. In addition, we demonstrate that mekk1 and mpk4 single-mutant plants have significantly different phenotypes. mekk1 plants are defective for lateral root...
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