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Article

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

12 Jun 2007

Abstract excerpt

ABSTRACT Mutations in PINK1 cause the mitochon‐drial‐related neurodegenerative disease Parkinson's. Here we investigate whether obesity, type 2 diabetes, or inactivity alters transcription from the PINK1 locus. We utilized a cDNA‐array and quantitative real‐time PCR for gene expression analysis of muscle from healthy volunteers following physical inactivity, and muscle and adipose tissue from nonobese or obese...

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PMID: 17567565
DOI: 10.1096/fj.07-8520com

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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