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Article

Molecular and cellular function of ALS2/alsin: implication of membrane dynamics in neuronal development and degeneration.

Neurochemistry international - 1 Jan 2000

Hadano Shinji, Kunita Ryota, Otomo Asako, Suzuki-Utsunomiya Kyoko, Ikeda Joh-E

Abstract excerpt

ALS2 is a causative gene for a juvenile autosomal recessive form of motor neuron diseases (MNDs), including amyotrophic lateral sclerosis 2 (ALS2), juvenile primary lateral sclerosis, and infantile-onset ascending hereditary spastic paralysis. These disorders are characterized by ascending degeneration of the upper motor neurons with or without lower motor neuron involvement. Thus far, a total of 12 independent...

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Source

Identifiers

PMID: 17566607
DOI: 10.1016/j.neuint.2007.04.010

Genes

ALS2
RCC1
SOD1

Provenance

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Related research

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Molecular and cellular function of ALS2/alsin: implication of membrane dynamics in neuronal development and degeneration.PMID 17566607Read ↗

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