Article
Scrapie: uncertainties, biology and molecular approaches.
Biochimica et biophysica acta - 1 Jun 2007
Hunter Nora
Abstract excerpt
The study of the biology of scrapie in sheep is irretrievably associated with the genetics of the PrP gene in sheep. Control of susceptibility and resistance is so closely linked to certain alleles of the sheep PrP gene that no review on scrapie can avoid PrP genetics. Before the importance of PrP protein was discovered and before the influence of the gene itself on disease incidence was understood, it was clear...
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