Article
In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes.
The Journal of antimicrobial chemotherapy - 1 Aug 2007
Mushtaq Shazad, Warner Marina, Ge Yigong, Kaniga Koné, Livermore David M
Abstract excerpt
BACKGROUND: Ceftaroline (PPI-0903M, T-91825) is a novel cephalosporin, administered as an N-phosphono prodrug. We investigated its in vitro activity and resistance selection potential. METHODS: MICs were determined by CLSI agar dilution, but with varied inocula. Mutant selection was investigated...
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