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Article

In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes.

The Journal of antimicrobial chemotherapy - 1 Aug 2007

Mushtaq Shazad, Warner Marina, Ge Yigong, Kaniga Koné, Livermore David M

Abstract excerpt

BACKGROUND: Ceftaroline (PPI-0903M, T-91825) is a novel cephalosporin, administered as an N-phosphono prodrug. We investigated its in vitro activity and resistance selection potential. METHODS: MICs were determined by CLSI agar dilution, but with varied inocula. Mutant selection was investigated in single- and multi-step procedures. RESULTS: MICs for methicillin-resistant Staphylococcus aureus (MRSA) were 0.5-2...

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Identifiers

PMID: 17548456
DOI: 10.1093/jac/dkm150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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