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Article

Antimicrobial activity of ceftaroline against methicillin-resistant Staphylococcus aureus (MRSA) isolates collected in 2013-2014 at the Geneva University Hospitals.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Feb 2017

Andrey D O, François P, Manzano C, Bonetti E J, Harbarth S, Schrenzel J, Kelley W L, Renzoni A

Abstract excerpt

Ceftaroline is a broad-spectrum antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA) strains. Ceftaroline susceptibility of an MRSA set archived between 1994 and 2003 in the Geneva University Hospitals detected a high percentage (66 %) of ceftaroline resistance in clonotypes ST228 and ST247 and correlated with mutations in PBP2a. The ceftaroline mechanism of action is based on the...

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Identifiers

PMID: 27744604
DOI: 10.1007/s10096-016-2807-5
PMCID: PMC5253141

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