Article
Genomic imprinting and the expression of affect in Angelman syndrome: what's in the smile?
Journal of child psychology and psychiatry, and allied disciplines - 1 Jun 2007
Oliver Chris, Horsler Kate, Berg Katy, Bellamy Gail, Dick Katie, Griffiths Emily
Abstract excerpt
BACKGROUND: Kinship theory (or the genomic conflict hypothesis) proposes that the phenotypic effects of genomic imprinting arise from conflict between paternally and maternally inherited alleles. A prediction arising for social behaviour from this theory is that imbalance in this conflict resulting from a deletion of a maternally imprinted gene, as in Angelman syndrome (AS), will result in a behavioural phenotype...
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