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Article

Invasion of HEp-2 cells by strains of Salmonella typhimurium of different virulence in relation to gastroenteritis.

Journal of medical microbiology - 1 Dec 1991

Douce G R, Amin I I, Stephen J

Abstract excerpt

Experiments to measure the invasiveness of seven strains of Salmonella typhimurium for HEp-2 cells showed that high inocula (100 bacteria/HEp-2 cell), as used by most workers to synchronise events and to increase the number of bacteria which invade, resulted in recovery of significantly less than 1% of the original inoculum after treatment with gentamicin to kill extracellular bacteria. Also, the cell culture...

Topics

Bacterial Adhesion
Cells, Cultured
Centrifugation
Colony Count, Microbial
Epithelium
Fetal Blood
Gastroenteritis
Humans
Intestinal Mucosa
Phenotype
Reproducibility of Results

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Salmonella Infections

Salmonella typhimurium

Time Factors

Virulence

Source

Identifiers

PMID: 1753393
DOI: 10.1099/00222615-35-6-349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1753393-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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