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Article

Invasion by Salmonella typhimurium is affected by the direction of flagellar rotation.

Infection and immunity - 1 Jun 1992

Jones B D, Lee C A, Falkow S

Abstract excerpt

When grown aerobically, Salmonella typhimurium exhibits a low level of entry into tissue culture cells. We have isolated an S. typhimurium Tn10 mutant which, when grown under aerobic conditions, efficiently invades HEp-2 cells. Sequencing of S. typhimurium DNA adjacent to the site of the Tn10 element showed that the insertion disrupted transcription of the aspartate receptor gene, tar. Polar effects of the...

Topics

Animals
Cells, Cultured
Chemotaxis
Female
Flagella
Mice
Mice, Inbred BALB C
Mutation
Phenotype
Rotation
Salmonella typhimurium
Virulence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1587617
DOI: 10.1128/iai.60.6.2475-2480.1992
PMCID: PMC257184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1587617-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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