Long term neuropsychological outcome after head injury: relation to APOE genotype.

doi:10.1136/jnnp.74.8.1047

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Article

Long term neuropsychological outcome after head injury: relation to APOE genotype.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 2003

Millar K, Nicoll J A R, Thornhill S, Murray G D, Teasdale G M

Abstract excerpt

BACKGROUND: Existing evidence suggests that some patients who sustain a head injury suffer cognitive decline many years later, and that head injury and possession of the APOE epsilon 4 allele are each risk factors for Alzheimer's disease. OBJECTIVE: To determine whether late cognitive decline after head injury is more prevalent among carriers of APOE epsilon 4. METHODS: A database of head injured patients was...

Topics

Adolescent
Adult
Aged
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Brain Injury, Chronic
Child
Child, Preschool
Cognition Disorders
Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Disease Progression

Female

Follow-Up Studies

Genetic Predisposition to Disease

Genotype

Glasgow Outcome Scale

Humans

Source

Open in PubMed Open full text

Identifiers

PMID: 12876232
DOI: 10.1136/jnnp.74.8.1047
PMCID: PMC1738588

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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