Article
Individual-specific patterns of human variable genomic regions detected by a DNA probe from the HIV-1 env gene.
Biomedical science - 1 Jan 1991
Rogaev E I, Shlenskii A B, Spoode AYa
Abstract excerpt
It was postulated that similar genetic elements that are 'hot spots' for genetic variation might exist in both the HIV-1 and the human genome. To test this possibility a short repeated sequence from a region of variability in the HIV-1 glycoprotein (env) gene was amplified and used as a probe for blot hybridization with human genome DNA. Human genomic regions were hybridized and characterized by a set of...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- DNA Probes
- DNA, Viral
- Genes, env
- Genetic Variation
- Genome, Viral
- HIV-1
- Humans
- Molecular Sequence Data
- Polymorphism, Genetic