[Genetic aspects of obesity].

Abstract excerpt

Genetic, specifically monogenic, obesity must be suspected: in cases of early severe obesity, developing in the first months of life; in cases of severely abnormal dietary behavior; in cases of associated endocrine abnormalities or pigmentation disorders; in cases of parental consanguinity. Mutations of the MC4R gene are the leading cause of oligogenic obesity. Discovery of a mutation of the MC4R gene furnishes a...

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