Gene-environment interactions in the skeletal response to nutrition and exercise during growth.

Abstract excerpt

The amount of bone mineral mass acquired at the end of growth, the so-called 'peak bone mass', is considered to be a major risk factor for the occurrence of fragility fractures during adult life. Many interrelated factors can influence the accumulation of bone mass during growth, including genetics, sex, ethnicity, nutrition (e.g. calcium, vitamin D, protein), hormonal factors (e.g. sex steroids, insulin-like...

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