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Article

Genetic diversity and drug resistance mutations in HIV type 1 from untreated patients in Bamako, Mali.

Antiviral therapy - 1 Jan 2007

Derache Anne, Traore Ousmane, Koita Victoria, Sylla Aliou, Tubiana Roland, Simon Anne, Canestri Ana, Carcelain Guislaine, Katlama Christine, Calvez Vincent, Cisse Mamadou, Marcelin Anne-Geneviève

Abstract excerpt

OBJECTIVE: To determine the genetic diversity of HIV-1 reverse transcriptase (RT) and protease sequences and the presence of mutations linked to antiretroviral (ARV) resistance in treatment-naive, HIV-1-infected individuals living in Mali. METHODS: Ninety-eight samples from ARV drug-naive, HIV-1-infected patients were collected in one clinical centre in Bamako, Mali in 2005. RT and protease genes were sequenced...

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PMID: 17503757

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