Article
Sequence analysis of the cystic fibrosis gene in patients with disseminated bronchiectatic lung disease. Application in the identification of a cystic fibrosis patient with atypical clinical course.
Klinische Wochenschrift - 16 Sept 1991
Poller W, Faber J P, Scholz S, Olek K, Müller K M
Abstract excerpt
The diagnosis of classical cystic fibrosis (CF) is easily made by clinical assessment alone, but may be missed or delayed in cases with an atypical clinical course. In a recent major study the age at diagnosis varied between 2 months and 47 years. For diagnostic purposes we have investigated the...
Topics
- Adult
- Base Sequence
- Blood Proteins
- Bronchiectasis
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- DNA
- Female
- Gene Amplification
- Genetic Carrier Screening
- Genotype
- Humans
- Lung Diseases, Obstructive
- Male
- Molecular Sequence Data
- Polymerase Chain Reaction
- Tomography, X-Ray Computed