Article
Genetic determinants of airways' colonisation with Pseudomonas aeruginosa in cystic fibrosis.
Lancet (London, England) - 23 Jan 1993
Kubesch P, Dörk T, Wulbrand U, Kälin N, Neumann T, Wulf B, Geerlings H, Weissbrodt H, von der Hardt H, Tümmler B
Abstract excerpt
Exocrine pancreatic insufficiency and lung infection with Pseudomonas aeruginosa are major features of cystic fibrosis (CF). This monogenic disease is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. 267 children and adolescents with CF who were regularly seen at the...
Topics
- Adolescent
- Adult
- Causality
- Child
- Child, Preschool
- Chronic Disease
- Colony Count, Microbial
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Evaluation Studies as Topic
- Female
- Gene Frequency
- Genotype
- Germany
- Heterozygote
- Homozygote
- Humans
- Incidence