Article
Mitochondrial DNA-related disorders.
Bioscience reports - 1 Jun 2007
Mancuso Michelangelo, Filosto Massimiliano, Choub Anna, Tentorio Marta, Broglio Laura, Padovani Alessandro, Siciliano Gabriele
Abstract excerpt
Mitochondrial diseases are a group of disorders due to a mitochondrial respiratory chain deficiency. They may depend on mitochondrial genome (mtDNA-related disorders) as well as on a nuclear genome defect (nDNA-related disorders). mtDNA-related disorders encompass an increasing number of clinical pictures associated with more than 250 different provisional or confirmed pathogenic changes in mtDNA. Although some...
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