Article
Resistance is non-futile: resistance to Cry5B in the nematode Caenorhabditis elegans.
Journal of invertebrate pathology - 1 Jul 2007
Barrows Brad D, Griffitts Joel S, Aroian Raffi V
Abstract excerpt
The nematode, Caenorhabditis elegans, can be mutated to resistance to the Cry5B toxin of Bacillus thuringiensis. By cloning and characterization of these C. elegans resistance genes, we have determined that a major mechanism by which C. elegans resists Cry5B is by loss of function mutations in any one of four gylcosyltransferase genes that glycosylate glycolipids specific to arthropods. Without correct...
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