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Article

Genotype and phenotype correlations in congenital glaucoma.

Transactions of the American Ophthalmological Society - 1 Jan 2006

Hollander David A, Sarfarazi Mansoor, Stoilov Ivaylo, Wood Irmgard S, Fredrick Douglas R, Alvarado Jorge A

Abstract excerpt

PURPOSE: To determine whether there is a correlation among mutations in the cytochrome P450 1B1 gene (CYP1B1), the degree of angle dysgenesis observed histologically, and disease severity in congenital glaucoma. METHODS: Direct DNA sequencing was utilized to screen six unrelated children with congenital glaucoma, each set of parents, and all siblings for CYP1B1 mutations. Specimens of the anterior chamber angle...

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Share to Cytochrome P-450 CYP1B1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17471339
PMCID: PMC1809895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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