Article
Long-acting beta2-adrenoceptor agonists: a smart choice for asthma?
Trends in pharmacological sciences - 1 Jun 2007
Lipworth Brian J
Abstract excerpt
An endogenous defect in beta(2)-adrenoceptors that results in impaired relaxation of airway smooth muscle was originally proposed as a putative underlying cause of the asthmatic condition. Short-acting beta(2)-adrenoceptor agonists such as salbutamol are still recommended for relieving acute episodes of bronchial smooth muscle spasm. Twice-daily long-acting beta(2)-adrenoceptor agonists (LABAs) such as salmeterol...
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