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Article

Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation.

The Journal of physiology - 1 Jul 2007

Subramanian Veedamali S, Mohammed Zainab M, Molina Andres, Marchant Jonathan S, Vaziri Nosratola D, Said Hamid M

Abstract excerpt

Retinal abnormality and visual disturbances occur in thiamine-responsive megaloblastic anaemia (TRMA), an autosomal recessive disorder caused by mutations in the human thiamine transporter-1 (hTHTR-1). Human retinal pigment epithelial cells play a pivotal role in supplying thiamine to the highly metabolically active retina but nothing is known about the mechanism, regulation or biological processes involved in...

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Identifiers

PMID: 17463047
DOI: 10.1113/jphysiol.2007.128843
PMCID: PMC2075275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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