Article
Elevated interleukin-4 expression in severe recurrent hepatitis C virus after liver transplantation.
Transplantation - 15 Apr 2007
Dharancy Sébastien, Podevin Philippe, Aoudjehane Lynda, Batteux Frédéric, Rosenberg Arielle R, Soubrane Olivier, Calmus Yvon, Conti Filomena
Abstract excerpt
BACKGROUND: Chronic hepatitis C virus (HCV) is usually associated with high levels of hepatic interleukin (IL)-2 and low levels of IL-4 transcripts. HCV frequently recurs after liver transplantation, and its course is accelerated in this setting. We compared in situ expression of IL-2 and IL-4 in transplanted and nontransplanted patients with HCV. METHODS: A total of 74 liver biopsy specimens were studied; 52...
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