Article
Investigation of variation in SNAP-25 and ADHD and relationship to co-morbid major depressive disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2007
Kim J W, Biederman J, Arbeitman L, Fagerness J, Doyle A E, Petty C, Perlis R H, Purcell S, Smoller J W, Faraone S V, Sklar P
Abstract excerpt
Synaptosomal-associated protein of 25 kDa (SNAP-25), a protein involved in presynaptic neurotransmitter release, is a candidate gene for attention deficit/hyperactivity disorder (ADHD). Previous investigators have reported association initially with two single nucleotide polymorphisms (SNPs) (rs3746544, rs1051312) and their associated haplotypes. Subsequently, additional SNPs across the region were also reported...
Read the complete abstract on PubMed