Article
Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment.
Current diabetes reports - 1 Dec 2011
Greeley Siri Atma W, Naylor Rochelle N, Philipson Louis H, Bell Graeme I
Abstract excerpt
There has been major progress in recent years uncovering the genetic causes of diabetes presenting in the first year of life. Twenty genes have been identified to date. The most common causes accounting for the majority of cases are mutations in the genes encoding the two subunits of the ATP-sensitive potassium channel (K(ATP)), KCNJ11 and ABCC8, and the insulin gene (INS), as well as abnormalities in chromosome...
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