Article
Investigation of endothelin-1 type A receptor gene polymorphism (-231 G > A) in preeclampsia susceptibility.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Feb 2007
Lisi Veronica, Paternoster Delia M, Stecca Anna, Micciché Flavia, Fantinato Sara, Leon Alberta, Damante Giuseppe, Fabbro Dora, Clementi Maurizio
Abstract excerpt
OBJECTIVE: Preeclampsia is considered as a multifactorial disorder with a genetic predisposition. Alterations in the endothelin-1 (ET-1) system are considered to take part in triggering the vasoconstriction seen in preeclampsia. METHODS: In order to investigate the possible association of the -231 G > A polymorphism in the endothelin-1 type A receptor gene (EDNRA), previously shown to be associated with other...
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