Article
Vesicle formation from the nuclear membrane is induced by coexpression of two conserved herpesvirus proteins.
Proceedings of the National Academy of Sciences of the United States of America - 24 Apr 2007
Klupp Barbara G, Granzow Harald, Fuchs Walter, Keil Günther M, Finke Stefan, Mettenleiter Thomas C
Abstract excerpt
Although the nuclear envelope is a dynamic structure that disassembles and reforms during mitosis, the formation of membranous vesicles derived from the nuclear envelope has not yet been described in noninfected cells. However, during herpesvirus maturation, intranuclear capsids initiate transit to the cytosol for final maturation by budding at the inner nuclear membrane. Two conserved herpesvirus proteins are...
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