Article
Evaluation of mathematical models for breast cancer risk assessment in routine clinical use.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jun 2007
Fasching Peter A, Bani Mayada R, Nestle-Krämling Carolin, Goecke Tim O, Niederacher Dieter, Beckmann Matthias W, Lux Michael P
Abstract excerpt
Chemoprevention, prophylactic surgery, and intensified screening can be offered to patients with an increased lifetime risk, p(life), for breast cancer. Estimation of p(life) includes BRCA analysis and risk estimation based on individual risk factors and family history. MENDEL and BRCAPRO are models that estimate the probability of BRCA1/2-mutations, p(mut), and p(life). In this study, the models are compared...
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