Article
Genetic and proteomic characterization of rifaximin resistance in Bifidobacterium infantis BI07.
Research in microbiology - 1 May 2007
Vitali Beatrice, Turroni Silvia, Dal Piaz Fabrizio, Candela Marco, Wasinger Valerie, Brigidi Patrizia
Abstract excerpt
Rifaximin resistance in the probiotic strain Bifidobacterium infantis BI07 was studied to assess the use of an antibiotic-probiotic combination for clinical management of intestinal disorders. A rifaximin-resistant mutant was selected and a 129 bp core region of the rpoB gene was sequenced and compared with the respective sequence of the sensitive clone. A miss-sense mutation of codon 513, producing the...
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