Article
A genetic linkage map of human chromosome 20 composed entirely of microsatellite markers.
Genomics - 1 Feb 1992
Hazan J, Dubay C, Pankowiak M P, Becuwe N, Weissenbach J
Abstract excerpt
Twenty-six (CA)n polymorphic microsatellites were isolated from a flow-sorted chromosome 20 library. To reduce the number of sequencing gels, these microsatellites were genotyped on 15 CEPH families using a procedure derived from the multiplex sequencing technique of G. M. Church and S. Kieffer-Higgins (1988, Science 240:185-188). A primary map with a strongly supported order was constructed with 15 (CA)n...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 20
- DNA, Satellite
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male
- Polymerase Chain Reaction
- Polymorphism, Genetic
