Article
In silico segmentations of lentivirus envelope sequences.
BMC bioinformatics - 21 Mar 2007
Boissin-Quillon Aurélia, Piau Didier, Leroux Caroline
Abstract excerpt
BACKGROUND: The gene encoding the envelope of lentiviruses exhibits a considerable plasticity, particularly the region which encodes the surface (SU) glycoprotein. Interestingly, mutations do not appear uniformly along the sequence of SU, but they are clustered in restricted areas, called variable (V) regions, which are interspersed with relatively more stable regions, called constant (C) regions. We look for...
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